Resources  email page print page Basic Information Introduction and Types of Depression Major Depression and other Unipolar DepressionsClassic Symptoms of Major DepressionUnderstanding Mood Episodes in DepressionThe Course of Major DepressionDSM Specifiers for Major DepressionPrevalenceFormal DSM Diagnoses for Other Depressive Mood DisordersSymptoms - Dysthymic DisorderFormal DSM Diagnoses Continued Related Disorders / Conditions Other Conditions Related to DepressionMajor Depression Related Conditions ContinuedMajor Depression Related Conditions ConclusionThe Far Reaches of Depression Historical and Current Understandings Historical Understandings of DepressionHistorical Understandings of Depression ContinuedCurrent Understandings of Major Depression - Biopsychosocial ModelCurrent Understandings of Major Depression - Diathesis-Stress Model Biology, Psychology and Sociology Biology of Depression - NeurotransmittersBiology of Depression - Neuroplasticity and EndocrinologyBiology of Depression - Genetics and ImagingBiology of Depression - PsychoneuroimmunologyPsychology of Depression- Psychodynamic TheoriesPsychology of Depression- Behavioral TheoriesCognitive Theories of Major Depression - Aaron BeckCognitive Theories of Major Depression - Ellis and BanduraCognitive Theories of Major Depression - SeligmanSociology of Depression - Effects of CultureSocial and Relational Factors in Major DepressionLifestyle Factors and Environmental Causes of Major Depression Treatment - Medication and Psychotherapy Treatment: When to Seek Professional Help and Where to Find Help for Major DepressionMeasuring DepressionClinician-Rated and Self-Report Questionnaires/Tests for Major DepressionModes of TreatmentMedications for Major DepressionAntidepressants for Major Depression - SSRIsAntidepressants for Major Depression - SSNIsAntidepressants for Major Depression - With Children, TCAs, and MAOIsMood Stabilizers for Major DepressionNon-pharmaceutical Medical Therapies for Major DepressionPsychotherapy - Evidence-Based Treatments for Major DepressionCognitive Behavioral Therapy for Major DepressionCognitive Behavioral Therapy for Major Depression ContinuedInterpersonal Therapy for Major DepressionOther Forms of Psychotherapy for Major Depression - Behavior TherapyOther Forms of Psychotherapy for Major Depression - Psychodynamic TherapyOther Forms of Psychotherapy for Major Depression - Group, Family and Couples Therapy Alternative Medicine and Self-Help Resources Complementary and Alternative Treatments for Major DepressionMajor Depression and St. John's WortMajor Depression and ExerciseMajor Depression and Omega 3 Fatty AcidsMajor Depression Serotonin Precursors: SAMeMajor Depression Serotonin Precursors: 5-HTPLess Well-Studied CAM Remedies For Depression - B-Vitamins and Traditional Chinese MedicineLess Well-Studied CAM Remedies For Depression - Ayurveda and HomeopathySelf-Help Methods for Major Depression Community and On-line Self-Help Resources for Major Depression Depression Reading List Special Issues Further Observations Regarding Major Depression Treatment and Special Issues - SuicideSpecial Issues - Severe Depression, Dual Depression and Dual Diagnosis References Depression Article References More Information Aging and DepressionAntidepressants No Better Than Placebo Says A New Study, But It's Really More Complicated Than That... Blunt InstrumentsBrain Neuroplasticity and Treatment Resistant DepressionComing Out of the Depression ClosetCosmo Magic to Cyclothymic: Highs, Lows and States of FlowDepression and CancerDepression and DiabetesDepression and Heart DiseaseDepression and HIV/AIDSDepression and ParkinsonsDepression and StrokeDepression and WomenDepression, ADHD, Psychotherapy and MedicationDysthymic Disorder SymptomsElliott Smith and the gift of Vulnerability MusicFeeling Good, It's Not Just In the BrainGoing Postal: The Road to Depression and SalvationGuest Editorial: Celeb Feud Brought Up Critical IssuesHelping Children Understand and Cope with Parental DepressionListening to Readers on Prozac, Depression & the Medical System: Part IListening to Readers on Prozac, Depression & the Medical System: Part IIMajor Depression SymptomsMen and DepressionNational Depression Screening Day, Thursday October 8, 2009Older Adults: Depression and Suicide FactsOrganizationsPost Partum Depression and The Importance of SleepReader Feedback on the Depression SeriesRunning On FiftySt. John's Wort FAQStudents and College, A Stressful Time of Life: Parents and Students BewareSymptoms of Depressive DisordersThe Biochemical - Psychosexual Revolution: Getting Up and Close while Being Down and OutThe Existential Crisis, Depression, Anxiety and MortalityThe Liberating and Entangling Webs of Technology, Depression and ProzacThe Long Term Effects of BullyingTop Twelve Tips for Beating (Mostly) Moderate Chronic Clinical DepressionTreatmentTreatment 1 of 2Treatment 2 of 2Unmasking Mental IllnessWebsitesWhat about the "milder" depression: Dysthymic disorder?Why People Might Use Anxiety to Avoid Depression: Part 2Why People Might Use Anxiety to Avoid Depression: What We Can Learn From a Wartime ExperienceWise Counsel Interview Transcript: An Interview with James Gordon MD on Mind Body Medicine and His Book 'Unstuck'Wise Counsel Interview Transcript: An Interview with with Ronald Dworkin, MD, Ph.D. on Artificial Happiness Tests Goldberg Depression Questionnaire Latest News Phone Care Can Help Combat Post-Heart Surgery DepressionClinical Trials Update: Nov. 16, 2009Depression Linked to Immune Response in PregnancyClinical Trials Update: Nov. 12, 2009Health Tip: Symptoms of Postpartum DepressionBrain Stimulation May Ease Treatment-Resistant DepressionClinical Trials Update: Nov. 9, 2009Adjunctive Psychotherapy for Depression StudiedDepression May Blur Memory of Aches and PainsCognitive Behavioral Therapy Helps Overcome Winter BluesPsychotherapy Beats Light Treatment for SADPhone Counseling for Depression Rings With PromiseDepression Often Goes Untreated in Working MomsConstant Light Linked to Symptoms of DepressionOmega-3 Augmentation of Antidepressant EvaluatedSuicidal Thoughts May Vary by AntidepressantImpact of Maternal Depression and Abuse on Children StudiedRecession Adds to Ranks of Americans With DepressionDepression, Anxiety May Raise Odds of ObesityTelephone Care and Therapy Help to Treat DepressionMother's Use of Antidepressant May Carry Risks for NewbornTroubled Minds Can Mean Wider WaistlinesTeens With ADHD, Depression Risk Internet AddictionAntidepressants May Be Linked to Birth ProblemsMediterranean Diet May Help Prevent DepressionAntidepressants Linked to Heart Defects in NewbornsPredicting Postpartum Depression May Be PossibleDrinking, Weight, Depression Linked in Young Women: StudyHealth Care Assistants May Be Useful in Depression CareDepression May Hasten Cancer DeathStudies Explore Genetic Factors Underlying DepressionSevere, Lasting Depression Tied to Heart Patient DeathsDepressed Teens Continue to Suffer into AdulthoodReport Addresses Depression Management in PregnancyDepression's Effect on Pleasure Is RealForeclosures Plunge People Into DepressionSuicide Risk With Antidepressants Falls With AgeCombo Treatment May Ease Depression After StrokeAntidepressant Use in U.S. Has Almost DoubledCan Children Headed for Teen Depression Be Spotted Early?Primary Care Identification of Depression ExaminedGloomy Days Dim Cognitive Powers of the DepressedDepression Poses Pregnancy RisksDepression, Anxiety Bad for the HeartStudy Refutes Depression Gene FindingDrug May Stem Slide Into Alzheimer's for SomeEffects of Depression on Families Need to Be AddressedIf Mom or Dad Is Depressed, Kids Need Help TooEarly Bedtime May Help Stave Off Teen DepressionNew Program May Help Teens at High Risk for Depression Questions and Answers Help Me Please. What is Going On With Me?I'm Afraid I'm Going CrazyI Don't Know What To DoAm I Wallowing in Depression?AngerSexual Abuse and Its Effects on Relationships AfterwardsWhat Is Wrong with Me, Doc? HelpDBSAm I Suffering a Kind of Psychological Problem? Blog Entries Depression, ADHD, Psychotherapy and MedicationKeeping You Sane: Do You Need a Day Out? Exploring the Upside of ADHDHow to Gain Control of Your Mind, Instead of Your Mind Controlling YouWhat You Need to Know about H1N1 and DepressionMindfulness and ADHD: A Tip from Dr. Lidia ZylowskaFreedom from Your Anxious MindThe Existential Crisis, Depression, Anxiety and MortalityADHD - Breaking the Cycle of ShameFeeling Good, It's Not Just In the BrainAre You Wired to Worry? Children, ADHD and Stimulant MedicationNational Depression Screening Day, Thursday October 8, 2009Mental Health: Our Troubled TeenagersDepression and Its MeaningsTeenage Depression and Consequences5 Steps to Emotional Freedom: Placebo or Panacea?Couples Therapy for Robert and Julia (Romeo and Juliet)New Research: Mindfulness-Based Program as Effective as Antidepressant MedicationAnxiety as a Defense Against Depression: Part 7Students and College, A Stressful Time of Life: Parents and Students BewareAnxiety as a Defense Against Depression: Part 6Brain Neuroplasticity and Treatment Resistant DepressionWhy People Might Use Anxiety to Avoid Depression: Part 5Feeling Stuck? Two Things You Need to Know to Make a Change Why People Might Use Anxiety to Avoid Depression: Part 4Childhood, Parental Loss and DepressionOne Strategy You Need to Know for Bipolar DisorderWhy People Might Use Anxiety to Avoid Depression: Part 3Psychiatric Meds: The Personal Debate Over UseWhy People Might Use Anxiety to Avoid Depression: Part 2Are You at Risk for Depression? Here's One Way to Find OutWhat about the "milder" depression: Dysthymic disorder?Why People Might Use Anxiety to Avoid Depression: What We Can Learn From a Wartime ExperienceBipolar Mood Swings? 4 Steps to Nip Them in the BudElisha Goldstein's Top 10 Mental Help Blog Posts3 Steps Out of Helplessness Post Partum Depression and The Importance of Sleep"The Big Emptiness": Hoarding, OCD, Depression and the Quest for MeaningFeeling Depressed? 3 Steps to HappinessDoes Psychotherapy Help Everyone?Of Parking Lots, Stress, Life and PsychotherapyFeeling Stuck with Anxiety or Depression? Try this Today! Catastrophizing Controlling Your Life: 3 Steps to Break FreeTeenagers and Depression: Their Families and PsychotherapyMeaning in Life: What Golf Balls Can Teach UsPeace in Oneself, Peace in the WorldWake Up to What Makes You Happy!Want Mental Health? Lessons from a KingKristie Alley and the Problem of Obesity and DietingHandling Difficult Emotions: The Path Less TraveledCan Blogs Really Help? Making Friends, A Matter of Where You Live?3 Ways to Stay Up in a Depressed Work EnvironmentOne Strategy to be More Successful Day to DayLife Feel Overwhelming? Lessons From a DishwasherWork Place Climate, Depression and Job SearchingVegetarian Diets May Harbor Eating Disordered Youngsters: This is it! Letting Go of Daily StruggleCognitive Distortions, also known as To Do: 3 Steps to Healing When You're Feeling Blue Depression: How We Get Stuck and What Can HelpYoung Yet Sad: The Social PhobicAn Interview with Thomas Joiner, Ph.D. on Why People Commit SuicideAlcohol as the Cause of Depression?Compassion: The Missing LinkBreak Free from the Mental Recession or Depression by Doing LessDepression and MarriageDementia and Neuroplasticity: What Might Help TodayHow this economic recession can pull you into an emotional recession without you even knowing it. 5 key steps that can helpHow Do You Feel After Sex?The Importance of Recognizing Childhood Successes at SchoolYour morning coffee or tea linked to happiness? Child Abuse and Chronic Fatigue SyndromeGrieving: 7 tips to get you through the holidaysFeeling Depressed? Here's 1 practice that could begin to turn it aroundTurn your sleep problems into a dream of the past! 5 tips from a Psychologist and mindfulness-based stress reduction teacherIs Happiness Contagious? Here is one way you can catch itSuicide: Does a Person Have the Right to Take His Own Life?An ancient way that has been called an "antidote" to fearSuspended From College For Expressing Suicidal Ideation (a reaction to an NPR radio story)I dare you: Using gratitude to support your mental healthIs the economy ruining your holiday season? 5 steps to a better holiday How you can be triggered into depression…without even knowing itHow to take advantage of the holidays and stave off stress, anxiety, and depressionA few clues that you’re entering into Seasonal Affective Disorder and what you can do about itA Natural Approach to Treating Depression Web SeriesBreaking down Barack Obama’s Psychology of Hope and how it may help you in trying times…Depression and SpiritualitySuicide Among White Middle Class IncreasesTranscranial Magnetic Stimulation device for treatment-resistant Major Depression just approved by the FDANational Depression Screening Day is just around the corner (October 10th!)Press "D" for Depression TherapyFew People Who Are Depressed Receive Mental Health Services"Guns and Suicide" article and Comments: What about the anger?An Interview with James Gordon, MD on Mind-Body Medicine and his book 'Unstuck'Regulating Brain Chemicals and Mental Illnesses with WINCS and DBSPleasure...Depression’s Kryptonite?World Suicide Prevention Day... 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You may have SAD (seasonal affective disorder)Diabetes, Depression and LifeElliott Smith and the gift of Vulnerability MusicWomen and DepressionMental Health, Memory and Social InteractionProblems Connected with Anti depressant medicationsPain and DepressionFibromyalgia, It is not just in your headA Combination of Cognitive Behavioral Therapy & Antidepressant Medication Works Best for Depressed AdolescentsDogs, Depression and Other Health Issues: Is there something to be gained from Illness?Anti depressants and young people: an issue revisitedAnniversary ReactionsBut, It Still Hurts: Pain-Depression-PainMassive update for our Depression topic centerThe Long Term Effects of BullyingCorrelation: Siblings and Depression?Interpersonal Therapy May Prevent Future Depressive EpisodesThe Negative Effects of Pain on DepressionDepression and Heart DiseaseOur Bipolar Topic Center has been UpdatedPODCAST: Dying To Live - Interview with a heart transplant patientNational Depression Screening Day is Tomorrow!Behavioral Therapy May Be Better Than Cognitive Therapy for Severe DepressionPerfectionism probably creates a Vulnerability for DepressionFeeling Depressed: Influenced by the Attitudes and Opinions of Others?Botox fights Depression?How Prozac gets its groove on.Chronic cortisol exposure causes mood disordersHeart Attacks and Young Women == DepressionSSRI antidepressants raise risk of premature birthAdult ADHD: Difficult to Diagnose and Often MisunderstoodNYTimes has story on Deep Brain Stim for DepressionBrain Scan Predicts Who Will Benefit From Cognitive TherapyThe Midlife Crisis: A Case of Extreme StressTreating Mother's Depression Helps Protect Their ChildrenMaintanence medications ward off senior depression relapseDepression predicts mental decline in seniorsUnmasking Mental IllnessBlunt InstrumentsCosmo Magic to Cyclothymic: Highs, Lows and States of FlowThe Biochemical - Psychosexual Revolution: Getting Up and Close while Being Down and OutListening to Readers on Prozac, Depression & the Medical System: Part IListening to Readers on Prozac, Depression & the Medical System: Part IIThe Liberating and Entangling Webs of Technology, Depression and ProzacTop Twelve Tips for Beating (Mostly) Moderate Chronic Clinical DepressionReader Feedback on the Depression SeriesComing Out of the Depression ClosetGoing Postal: The Road to Depression and SalvationRunning On Fifty Videos Behavior Therapy for DepressionAntidepressant MedicationsMajor Depression VideoAntidepressants VideoIf I Had - A Family Member with Psychotic Depression VideoThe Link Between Sleep and DepressionTreating Major DepressionShedding Light on Seasonal DepressionWhat is Depression?Separating Depression From Being BlueIs Your Child Depressed?When Winter Brings on More than the DoldrumsMeet Sue Bergeson: Depression and Bipolar Support AlliancePreparing for CrisisRising Above TragedyRole of Norepinephrine and Seratonin in DepressionChildren and AntidepressantsSymptoms of Childhood DepressionChildhood DepressionHow Did You Cope with Your Husband's DepressionHow Can Caregivers Help if Their Loved One is Depressed?Why Suicide Rates Are Higher than Homocide RatesDepression in TeensSeasonal Affective Disorder: One Woman's StoryPostpartum DepressionElderly DepressionGenetic Link to DepressionThe Link Between Stress and DepressionLight Therapy for Seasonal Affective Disorder (SAD)Tips for Coping with Antidepressant Side EffectsPost Holiday BluesCauses of Depression VideoDealing With Depression VideoWho Does Depression Affect VideoTreatment of Depression VideoSymptoms of Depression VideoTypes of Depression VideoLiving with Family with Depression VideoStrategies to Deal with Depression VideoDepression is a Serious Illness Video Links [1] Articles[2] Associations[13] Community[1] Government[42] Information[1] Journals[1] Other Sites[3] Research[1] Services[2] Self-Help[40] Videos[3] Personal Experiences[8] Blogs Book Reviews A Heart of StoneA Mood ApartA Philosophical DiseaseActive Treatment of DepressionAdolescent DepressionAgainst DepressionAn Unquiet MindBeating the BluesBefore ProzacBlaming the BrainCalm EnergyConquering Postpartum DepressionConquering the Beast WithinDamageDepressionDepression FalloutDepression in ContextDepression Is a ChoiceDepression, the Mood DiseaseDepression-Free for LifeDown Came the RainDysthymia and the Spectrum of Chronic DepressionsEmotional ClaustrophobiaEssential Psychopharmacology of Depression and Bipolar DisorderEverything Is FineExperiences of DepressionHandbook of DepressionHandbook of DepressionHistory of SuicideHow I Stayed Alive When My Brain Was Trying to Kill MeIn Pursuit of HappinessJourneys with the Black DogLifting DepressionLincoln's MelancholyLucy Sullivan Is Getting MarriedMalignant SadnessMindfulness-Based Cognitive Therapy for DepressionMood GenesMy DepressionNatural Healing for DepressionNew Hope for People with DepressionOn the Edge of DarknessOutsmarting DepressionOvercoming DepressionPotatoes Not ProzacProzac and the New AntidepressantsProzac BacklashProzac DiaryProzac NationPuppy Chow Is Better Than ProzacRaising a Moody ChildSelf-CoachingSongs from the Black ChairSpeaking of SadnessStudent DepressionSubordination and DefeatSunbathing in the RainSwing LowTalking Back to ProzacThe American Psychiatric Publishing Textbook of Mood DisordersThe Anatomy of MelancholyThe Anti-Depressant Fact BookThe Antidepressant EraThe BeastThe Bell JarThe CorrectionsThe Cruelty of DepressionThe Depressed ChildThe Depression CureThe Emotional RevolutionThe Family SilverThe Feeling Good HandbookThe Mood CureThe Nature of MelancholyThe Noonday DemonThe Postpartum EffectThe Secret Strength of DepressionThe Van Gogh BluesThe Van Gogh BluesUndercurrentsUnderstanding DepressionUndoing DepressionUnholy GhostUnstuckWhat the Birds SeeWhen a Parent is DepressedWhen Nothing Matters AnymoreWhen Words Are Not EnoughWhy Are You So Sad?Writing Through the Darkness Self-Help Groups BPSO (Bipolar Significant Others Bulletin Board)Dep-Anon

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THURSDAY, Nov. 5 (HealthDay News) -- Adjunctive psychotherapy added to antidepressant medications for patients with chronic depression did not increase the proportion of patients achieving remission, according to a study in the November issue of the Archives of General Psychiatry.

James H. Kocsis, M.D., of Weill Cornell Medical College in New York City, and colleagues treated chronically depressed patients using a two-phase treatment protocol with phase one consisting of an antidepressant medication used in accordance with a pharmacotherapy algorithm. After phase one, patients not achieving remission were randomized to 12 weeks of either continued medication and the addition of the cognitive behavioral analysis system of psychotherapy, continued medication and the addition of brief supportive psychotherapy, or optimized medication alone.

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Overall, the researchers found the mean Hamilton Scale for Depression (HAM-D) scores dropped from 25.9 to 17.7 among non-responders and from 15.2 to 9.9 among partial responders. However, there was no significant difference for the three phase two treatment strategies in terms of remission (15.0 percent), partial response (22.5 percent), non-response (62.5 percent), or HAM-D score changes.

"Although 37.5 percent of the participants experienced partial response or remitted in phase two, neither form of adjunctive psychotherapy significantly improved outcomes over that of a flexible, individualized pharmacotherapy regimen alone. A longitudinal assessment of later-emerging benefits is ongoing," the authors write.

Several authors reported financial relationships with the pharmaceutical industry. All study medications were donated by pharmaceutical companies.

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