What are the Dangers of Hydrocodone?
According to the Centers for Disease Control and Prevention, nearly 2 million Americans abused prescription painkillers in 2013, and 44 people die from an overdose every day.
Immediate Effects and Adverse Effects of Hydrocodone Use
Hydrocodone is the most widely prescribed, and also the most widely misused.
Among prescription painkillers, hydrocodone is the most widely prescribed, and also the most widely misused. Its high rate of abuse and risk for dependence make it crucial to better understand the risks associated with hydrocodone use.
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Hydrocodone is a type of drug known as a narcotic, or opioid—this is a type of drug that relieves pain by attaching itself to receptors in the brain and interfering with pain signaling.
Opioids can also affect parts of the brain related to reward and to breathing. Hydrocodone is the most widely prescribed opioid, and while it may be prescribed by itself, it’s also commonly combined with another painkiller called acetaminophen.
Some examples of common hydrocodone and acetaminophen combination drugs include Norco, Vicodin and Lortab.
Hydrocodone is used to relieve pain and sometimes coughing, and when it’s used correctly, it can be a valuable medical tool. However, it can cause other side effects, too.
Because of its effect on reward centers in the brain, hydrocodone’s immediate effects often include a rush of euphoria, which can be accompanied by drowsiness.
Users may also experience:
- Nausea.
- Vomiting.
- Dizziness.
- Itching.
- Constricted pupils or watery eyes.
Hydrocodone can also cause some cognitive effects, such as confusion, anxiety, or changes in mood.
Because hydrocodone affects parts of the brain that regulate breathing, it can also cause respiratory problems, such as tightness in the chest and slow or shallow breathing—especially if taken in quantities that exceed prescribed amounts.
These symptoms are classic signs of an overdose, along with:
- Clamminess.
- Convulsions.
- Loss of consciousness.
Hydrocodone overdose is extremely dangerous and can lead to death by respiratory depression, which is when a person’s breathing becomes inadequate.
Long-term Effects of Hydrocodone
Recently, the U.S. Drug Enforcement Administration reclassified hydrocodone combination products as Schedule II drugs, too, in the hopes of helping curb hydrocodone abuse.In addition to the risk of dependence, one major concern is the effect of hydrocodone use on pregnancy.
Individuals who use opioids for longer periods of time may be more likely to couple the drug with benzodiazepines, a class of drugs primarily used as sedatives. Combining drugs can increase the risk of overdose, which also becomes more likely the longer an individual has been using an opioid drug.

Call 1-888-993-3112Who Answers? to speak with a treatment support team member about your hydrocodone recovery options today.
Dependence and Withdrawal
How Addiction Changes Your Life
44 people die from a prescription painkiller overdose every day in the U.S.The Centers for Disease Control and PreventionMany people dealing with hydrocodone addiction already suffer from chronic pain—the reason they started taking the drug in the first place. In addition to the psychological difficulties of living with chronic pain, which is widely associated with depression, opioid addiction can increase the likelihood of developing a range of mood disorders, such as panic or depression.
Hydrocodone addiction can also lead some people to engage in uncharacteristic or illegal behavior, such as visiting more than one doctor and filling multiple pain prescriptions in different places. Over time, as tolerance starts to build, they may also take measures to boost their euphoric reaction to the drug by combining it with other substances.
Alcohol and benzodiazepines, such as Xanax, are sometimes used as a means to augment an opioid high—both particularly dangerous combinations.
Finally, the risk of overdose is a major concern for those addicted to hydrocodone, and for their families.
The fear of overdose can be a tremendous pressure on both the addicted individual and his or her loved ones.

Call 1-888-993-3112Who Answers? to hear more details about hydrocodone addiction treatment program options.
Mental Health Effects
Most research has focused broadly on opioid addiction, but many of these results will also apply specifically to hydrocodone dependence.
Research has shown that people with a prior history of alcohol or drug addiction are particularly vulnerable to opioid addiction.
Research has shown that people with a prior history of alcohol or drug addiction are particularly vulnerable to opioid addiction.
Certain mental health diagnoses may also be associated with an increased risk for drug misuse:
- Post-traumatic stress disorder (PTSD): This has been associated with an increased risk for opioid misuse and for adverse outcomes, such as accidents or overdose.
- Depression.
This may be problematic, because depression is common among people suffering from chronic moderate to severe pain, a condition hydrocodone is often used to treat.
On the other hand, dependence on opioids may also be responsible for bringing on a range of psychiatric problems.
Research has found that misuse of prescription opioids was associated with:
- Panic.
- Depression.
- Social phobia.