Symptoms of Depression
Depression: Major Depression & Unipolar Varieties
Basic Information

Major Depression Resources

Everyone has days where they feel blah, down, or sad. Typically, these feelings disappear after a day or two, particularly if circumstances change for the better. People experiencing the temporary "blues" don't feel a sense of crushing hopelessness or helplessness, and are able, for the most part, to continue to engage in regular activities. Prolonged anhedonia (the inability to experience pleasure), hopelessness, and failure to experience an increase in mood in response positive events rarely accompany "normal" sadness. The same may be said for other, more intense sorts of symptoms such as suicidal thoughts and hallucinations (e.g., hearing voices). Instead, such symptoms suggest that serious varieties of depression may be present, including the subject of this document: Major Depressive Disorder (MDD) or (more informally), Major Depression.

For people dealing with Major Depression, negative feelings linger, intensify, and often become debilitating.

Major Depression is a common yet serious medical condition that affects both the mind and body. It is a complex illness, creating physical, psychological, and social symptoms. Although informally, we often use the term "depression" to describe general sadness, the term Major Depression is defined by a formal...

 

 
Latest News
Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
Depression in Pregnancy May Lead to Antisocial Teens
Untreated, Mild May Become Major Depression
Internet Addicts More Prone to Depression
Genetic Variants in Depressed People Raise Suicide Risk
Clinical Trials Update: Feb. 1, 2010
Serotonergic Drugs May Delay Lactation
Antidepressants May Complicate Breast-Feeding
Clinical Trials Update: Jan. 25, 2010
Screening for Postpartum Depression Can Be Beneficial
Stress, Anxiety Can Up Risk of Depression in Pregnancy
Serotonin-1A Receptor Gene Linked to Depression
Clinical Trials Update: Jan. 19, 2010
Migraine, Depression May Have Genetic Link
Why Antidepressants Don't Work for Everyone
Clinical Trials Update: Jan. 12, 2010
Impact of Depression on Work Performance Measured
Risk Factors for Depression in Pregnancy Studied
Clinical Trials Update: Jan. 7, 2010
Lifestyle Reduces Depression in Breast Cancer Survivors
Racial Differences Seen for Depression Treatment
Erectile, Depression Issues Common in Heart Disease
Antidepressants Less Effective for Mild, Moderate Symptoms
Severely Depressed Gain Most from Antidepressants
New Approaches Could Bring Better Depression Treatments
Most Depressed Adults Going Without Treatment
Antidepressants Reduce Odds of Suicidal Teens' Readmission
Depressed People Can't Hold Onto Happiness
Antidepressants Not Found to Increase Heart Risk
Clinical Trials Update: Dec. 15, 2009
Antidepressants May Raise Women's Stroke Risk
SSRIs Linked to Upper Gastrointestinal Bleeding
Cognitive Behavioral Therapy Helps Elders With Depression
Blood Lead Levels Associated With Risk of Depression
Clinical Trials Update: Dec. 8, 2009
Antidepressants May Change Your Personality
Depression Linked to Poorer Spinal Surgery Outcomes
Study Calls Coverage of Antidepressants Insufficient
Clinical Trials Update: Dec. 7, 2009
Clinical Trials Update: Dec. 1, 2009
Fear of Anxiety May Lead to Depression
Depressed Nonresident Fathers Less Close to Sons
Seniors May Need Help Overcoming Holiday Blues
Depression May Up Death Risk to That of Smoking
Phone Care Can Help Combat Post-Heart Surgery Depression
Clinical Trials Update: Nov. 16, 2009
Depression Linked to Immune Response in Pregnancy
Clinical Trials Update: Nov. 12, 2009
Health Tip: Symptoms of Postpartum Depression
Brain Stimulation May Ease Treatment-Resistant Depression
 
Questions and Answers
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I Don't Know Anymore. Please Help.
I Think I am Gay and I Need Help to Convert to Heterosexual?
Breaking up With Bipolar
Depression - Blacking Out
He's Distant. Is he Leaving me?
My Boyfriend Saved Pictures of his Ex-Girlfriend on His Computer.
Restroom Phobia
What Is Wrong with Me?
Should I Seek Help?
When to Leave Therapy?
Help Me Please. What is Going On With Me?
I'm Afraid I'm Going Crazy
I Don't Know What To Do
Am I Wallowing in Depression?
Anger
Sexual Abuse and Its Effects on Relationships Afterwards
What Is Wrong with Me, Doc?
Help
DBS
Am I Suffering a Kind of Psychological Problem?
Attention Deficit and Depression
Do I Have an Eating Disorder?
Do you think I sound depressed? I don't understand what is going on
No Sex Drive
Is This Bi Polar?
Depressed 19 year old college student
Thoughts
Depression helps to contribute to my unemployment! - Paula
Will I ever feel normal?
I feel like I am going crazy
What is wrong with me?
I'm Scared
What Is Wrong with Me?
Cyclical Depression
Frightening thoughts - fear losing control - please help!
Anxious, depressed, confused, angry....the typical...
My depressed husband won't sleep with me. What should I do?
Giving Up - Dad of three - Sep 15th 2008
Counting ritual - Zami - Aug 30th 2008
dont understand me
Exercising violence in dreams
Swallowing fear
My husband wants to leave me
Is there help for a person who has always been a 'little depressed'
Depression Treatment
Please help.
Lovely, however... - Julie C. - Jul 14th 2008
I am really worried about my mental health (19yr old female)
Am I depressed?
Identity Confusion: I don't know what personality disorders I have
Do I Have Bipolar Dsorder?
Is there something wrong with me?
Will I Ever?
Worried about my son
Is There Help Out There? Lonely Mother of Three
Am I Depressed?
Help?
Major Depressive Disorder Severe with Psychotic Features
OCD- No feeling
Help!!!: Laci
Is the memory of my father dooming my relationship?
Worried about thoughts
How long will i be on medication for treatment of my depression
My Mother Won't Go For Depression Treatment!
Where do i start to get on the road to recovery
What is wrong with me?
Stuck in an on-again, off-again relationship for 10 years
Depression Treatment
How do I get my dr.s to understand and help me?
STUCK IN A RUT
What treatments are available after you've tried the medicines of last resort?
no one will help!
Should I seek help?
A fighting couple
Do I have a mental health problem?
Whats wrong with me?
depression and employment
how do you treat depression in teenager males?
Is it ok to feel this way?
Have DID: Getting Worse Not Better
Can we contact my mother's doctor?
anxiety or going crazy?
ADD, Tourettes or both?
Depressed
I think i'm lost?
Don't want to take meds
Will this ever end
Get Supported
Stages of Depression
Is there any help?
Can you help?
Dark Fantasies
Blood tests
Is it illusion or truth?
should a depressed person marry?
Dementia and Depression
Anger?
What type of exams can proven that a person has bipolar disorder?
Stuck in a mental rut...
Loss of Patience
i can't seem to get over any of this
Intrusive humiliating memories
Is there some way to deal with depression without meds?
losing personality wholness
What is the point of life?
No change is normal mood (e.g., Depression)
Lack of Personal Hygiene
Diagnosing Depression
Does untreated depression pass on to a fetus?
A Request for Help
Regular thoughts of killing myself
How do I help my depressed, unemployed mother
Angry at my doctor for prescribing so carelessly
I become very hostile towards myself
Coming to Terms With My Own Pathetic Existence
Do environmental factors hold a person back?
Tired of this Depression
Struggling With Feelings And Thoughts
Greatly Depressed
Is Depression Getting More Prevalent?
An Empty Shell
Helping My Husband
Inability To Express Myself
Non-medication Help For Depression
Suicidal
Sick Of Feeling This Way
Untrusting Patient
Depressed and Not Dating
Congenital Laziness
Moody Boyfriend
Electroconvulsive Therapy
Desperate
Frustrated and Sucked Dry
Too Young For Meds
Depressed Husband
Paranoid Depression
Self-Harming Attention Seeker
Did My Parents Make Me Like This?
Wild Mood Swings
A Wonderful Man
How Can I Become Less Depressed?
18, Sad and Hopeless
Should I Continue With Therapy?
Childhood Depression
Can I Help My Wife With Depression?
Prozac Questions
Approaching My Tightly Wound Depressed Attorney Brother
Brain Injury and Depression
No Compassion For Depression
Recurrent Depression
Meds Don't Seem To Work So Now What?
Pleasure-blind
Do People Recover From Depression?
Shy Dancer
Crying Is Behavior
Med Consult
Feeling Depressed and Insecure
Shyness And The Post Partum Blues
The Aftermath of Abuse
Do I Tell My Children I'm Depressed?
Now What?
Medicine Doesn't Work Anymore
Depressed
The First Time
Depressed Boyfriend
How Do I Leave?
Potentially Suicidal Boyfriend
Alternative Treatment
Bereavement and Grief
Paranoid Dad
Depression Affects The Entire Family
How Can I Stop Depression From Recurring?
Crohn's Disorder Side Effects
Is Paranoia A Destiny?
Post-Drinking Depression
Security Clearance and Depression
Can I Inherit Depression?
Two Clinicians
Depressed Spouse
Depression 101
Hypnosis?
Controlling, Disabled Husband
Are These Just Mood Swings
Drifting Apart?
Drinking. . .
A Mother Struggles with Depression
Marijuana and Depression
Overburdened Mom
Trashed House
Beautiful Dreamer
PMS Woes
Severely Depressed
Miss Lonely
Unhappy and In Therapy
He Won't Tell Me Why...
Lonely
Depression Affecting My Relationship
Lonesome
My Children Aren't Speaking..
My Wife is Depressed
My Boyfriend Is Depressed
Carolyn writes:
Parlante writes:
 
Weblog Entries
More Mindfulness Research for Anxiety and Depression: Here's the Rub
Valentines Day, How to Keep the Flame Alive
Alcoholic's Anonymous, Outcomes and New Research on Alcoholism
Depression, Anxiety and Pets
Thoughts are Not Facts: A Story Everyone Should Know
"I'm Singin in The Rain, Just Singin in the Rain, What a Wonderful Feelin, I'm Happy Again..."
Depression and the Elusiveness of Pleasure
The Stigma of "Disorder": Wisdom from Therese Borchard
Where There is Life, There is Hope, Depression and Why Suicide is Not an Option.
Walk To Washington: Raising Awareness about Major Depression
Research Suggests Mindfulness Reduces Bipolar Relapse
Sensory Defensiveness or Sensory Overload
Milder Depressions Don't Appear to Benefit From Antidepressant Treatment
Elisha Goldstein's Top 10 Blog Posts for 2009
Staying Sober: Dealing With Temptations
Troubled Marriages T.V. News Interview
Of Troubled Marriages, Sexual Compulsions and Depression
3 Steps to Mindfully Work with ADHD and Procrastination
How Your Mind Sabotages Your Best Intentions: 3 Steps to Breaking Free
Depression? Stress? How Sweet they Are? A Dissertation on Dark Chocolate
Depression, ADHD, Psychotherapy and Medication
Keeping You Sane: Do You Need a Day Out?
Exploring the Upside of ADHD
How to Gain Control of Your Mind, Instead of Your Mind Controlling You
What You Need to Know about H1N1 and Depression
Mindfulness and ADHD: A Tip from Dr. Lidia Zylowska
Freedom from Your Anxious Mind
The Existential Crisis, Depression, Anxiety and Mortality
ADHD - Breaking the Cycle of Shame
Feeling Good, It's Not Just In the Brain
Are You Wired to Worry?
Children, ADHD and Stimulant Medication
National Depression Screening Day, Thursday October 8, 2009
Mental Health: Our Troubled Teenagers
Depression and Its Meanings
Teenage Depression and Consequences
5 Steps to Emotional Freedom: Placebo or Panacea?
Couples Therapy for Robert and Julia (Romeo and Juliet)
New Research: Mindfulness-Based Program as Effective as Antidepressant Medication
Anxiety as a Defense Against Depression: Part 7
Students and College, A Stressful Time of Life: Parents and Students Beware
Anxiety as a Defense Against Depression: Part 6
Brain Neuroplasticity and Treatment Resistant Depression
Why People Might Use Anxiety to Avoid Depression: Part 5
Feeling Stuck? Two Things You Need to Know to Make a Change
Why People Might Use Anxiety to Avoid Depression: Part 4
Childhood, Parental Loss and Depression
One Strategy You Need to Know for Bipolar Disorder
Why People Might Use Anxiety to Avoid Depression: Part 3
Psychiatric Meds: The Personal Debate Over Use
Why People Might Use Anxiety to Avoid Depression: Part 2
Are You at Risk for Depression? Here's One Way to Find Out
What about the "milder" depression: Dysthymic disorder?
Why People Might Use Anxiety to Avoid Depression: What We Can Learn From a Wartime Experience
Bipolar Mood Swings? 4 Steps to Nip Them in the Bud
Elisha Goldstein's Top 10 Mental Help Blog Posts
3 Steps Out of Helplessness
Post Partum Depression and The Importance of Sleep
"The Big Emptiness": Hoarding, OCD, Depression and the Quest for Meaning
Feeling Depressed? 3 Steps to Happiness
Does Psychotherapy Help Everyone?
Of Parking Lots, Stress, Life and Psychotherapy
Feeling Stuck with Anxiety or Depression? Try this Today!
Catastrophizing Controlling Your Life: 3 Steps to Break Free
Teenagers and Depression: Their Families and Psychotherapy
Meaning in Life: What Golf Balls Can Teach Us
Peace in Oneself, Peace in the World
Wake Up to What Makes You Happy!
Want Mental Health? Lessons from a King
Kristie Alley and the Problem of Obesity and Dieting
Handling Difficult Emotions: The Path Less Traveled
Can Blogs Really Help?
Making Friends, A Matter of Where You Live?
3 Ways to Stay Up in a Depressed Work Environment
One Strategy to be More Successful Day to Day
Life Feel Overwhelming? Lessons From a Dishwasher
Work Place Climate, Depression and Job Searching
Vegetarian Diets May Harbor Eating Disordered Youngsters:
This is it! Letting Go of Daily Struggle
Cognitive Distortions, also known as
To Do: 3 Steps to Healing When You're Feeling Blue
Depression: How We Get Stuck and What Can Help
Young Yet Sad: The Social Phobic
An Interview with Thomas Joiner, Ph.D. on Why People Commit Suicide
Alcohol as the Cause of Depression?
Compassion: The Missing Link
Break Free from the Mental Recession or Depression by Doing Less
Depression and Marriage
Dementia and Neuroplasticity: What Might Help Today
How this economic recession can pull you into an emotional recession without you even knowing it. 5 key steps that can help
How Do You Feel After Sex?
The Importance of Recognizing Childhood Successes at School
Your morning coffee or tea linked to happiness?
Child Abuse and Chronic Fatigue Syndrome
Grieving: 7 tips to get you through the holidays
Feeling Depressed? Here's 1 practice that could begin to turn it around
Turn your sleep problems into a dream of the past! 5 tips from a Psychologist and mindfulness-based stress reduction teacher
Is Happiness Contagious? Here is one way you can catch it
Suicide: Does a Person Have the Right to Take His Own Life?
An ancient way that has been called an "antidote" to fear
Suspended From College For Expressing Suicidal Ideation (a reaction to an NPR radio story)
I dare you: Using gratitude to support your mental health
Is the economy ruining your holiday season? 5 steps to a better holiday
How you can be triggered into depression…without even knowing it
How to take advantage of the holidays and stave off stress, anxiety, and depression
A few clues that you’re entering into Seasonal Affective Disorder and what you can do about it
A Natural Approach to Treating Depression Web Series
Breaking down Barack Obama’s Psychology of Hope and how it may help you in trying times…
Depression and Spirituality
Suicide Among White Middle Class Increases
Transcranial Magnetic Stimulation device for treatment-resistant Major Depression just approved by the FDA
National Depression Screening Day is just around the corner (October 10th!)
Press "D" for Depression Therapy
Few People Who Are Depressed Receive Mental Health Services
"Guns and Suicide" article and Comments: What about the anger?
An Interview with James Gordon, MD on Mind-Body Medicine and his book 'Unstuck'
Regulating Brain Chemicals and Mental Illnesses with WINCS and DBS
Pleasure...Depression’s Kryptonite?
World Suicide Prevention Day... September 10, 2008
Mood Changes Linked To Seasonal Fluctuations in Serotonin
An Interview with Ronald Dworkin, MD, Ph.D. on Artificial Happiness (using antidepressants to mask ordinary unhappiness)
Is Chronic Pain and Depression destroying your life?
In Pursuit of Happiness, Part 3
Three things you can do immediately when you find yourself getting depressed
Why Is Happiness So Difficult to Achieve? Part 1
The Influence of Culture on the Expression of Depression
Low Self Esteem: Eating or Spending to Escape
Depression and Diabetes: A Deadly Combination
Mood Change Doesn't Happen Quickly
Life: Are We Listening and Living?
New Hope for People with Major Depression
Depression: A New Frontier in It's Treatment
Economic and Mental Depression
Whisk Those Blues Away
The Relationship Between Exercise and Mood
Antidepressants No Better Than Placebo Says A New Study, But It's Really More Complicated Than That...
Retail Therapy, Sadness and Spending: The Study Behind the Story
I'm So Bored!
Psychotherapy: A More than Oncer Per Week Commitment
Feeling down during the winter? You may have SAD (seasonal affective disorder)
Diabetes, Depression and Life
Elliott Smith and the gift of Vulnerability Music
Women and Depression
Mental Health, Memory and Social Interaction
Problems Connected with Anti depressant medications
Pain and Depression
Fibromyalgia, It is not just in your head
A Combination of Cognitive Behavioral Therapy & Antidepressant Medication Works Best for Depressed Adolescents
Dogs, Depression and Other Health Issues: Is there something to be gained from Illness?
Anti depressants and young people: an issue revisited
Anniversary Reactions
But, It Still Hurts: Pain-Depression-Pain
Massive update for our Depression topic center
The Long Term Effects of Bullying
Correlation: Siblings and Depression?
Interpersonal Therapy May Prevent Future Depressive Episodes
The Negative Effects of Pain on Depression
Depression and Heart Disease
Our Bipolar Topic Center has been Updated
PODCAST: Dying To Live - Interview with a heart transplant patient
National Depression Screening Day is Tomorrow!
Behavioral Therapy May Be Better Than Cognitive Therapy for Severe Depression
Perfectionism probably creates a Vulnerability for Depression
Feeling Depressed: Influenced by the Attitudes and Opinions of Others?
Botox fights Depression?
How Prozac gets its groove on.
Chronic cortisol exposure causes mood disorders
Heart Attacks and Young Women == Depression
SSRI antidepressants raise risk of premature birth
Adult ADHD: Difficult to Diagnose and Often Misunderstood
NYTimes has story on Deep Brain Stim for Depression
Brain Scan Predicts Who Will Benefit From Cognitive Therapy
The Midlife Crisis: A Case of Extreme Stress
Treating Mother's Depression Helps Protect Their Children
Maintanence medications ward off senior depression relapse
Depression predicts mental decline in seniors
Unmasking Mental Illness
Blunt Instruments
Cosmo Magic to Cyclothymic: Highs, Lows and States of Flow
The Biochemical - Psychosexual Revolution: Getting Up and Close while Being Down and Out
Listening to Readers on Prozac, Depression & the Medical System: Part I
Listening to Readers on Prozac, Depression & the Medical System: Part II
The Liberating and Entangling Webs of Technology, Depression and Prozac
Top Twelve Tips for Beating (Mostly) Moderate Chronic Clinical Depression
Reader Feedback on the Depression Series
Coming Out of the Depression Closet
Going Postal: The Road to Depression and Salvation
Running On Fifty
 
Tests
 
Videos
 
Links
 
Book Reviews
A Heart of Stone
A Mood Apart
A Philosophical Disease
Active Treatment of Depression
Adolescent Depression
Against Depression
An Unquiet Mind
Beating the Blues
Before Prozac
Blaming the Brain
Calm Energy
Conquering Postpartum Depression
Conquering the Beast Within
Damage
Depression
Depression Fallout
Depression in Context
Depression Is a Choice
Depression, the Mood Disease
Depression-Free for Life
Down Came the Rain
Dysthymia and the Spectrum of Chronic Depressions
Emotional Claustrophobia
Essential Psychopharmacology of Depression and Bipolar Disorder
Everything Is Fine
Experiences of Depression
Handbook of Depression
Handbook of Depression
History of Suicide
How I Stayed Alive When My Brain Was Trying to Kill Me
In Pursuit of Happiness
Journeys with the Black Dog
LifeForce Yoga to Beat the Blues--Level 1
LifeForce Yoga to Beat the Blues: Level 2
Lifting Depression
Lincoln's Melancholy
Lucy Sullivan Is Getting Married
Malignant Sadness
Mindfulness-Based Cognitive Therapy for Depression
Mood Genes
My Depression
Natural Healing for Depression
New Hope for People with Depression
On the Edge of Darkness
Outsmarting Depression
Overcoming Depression
Potatoes Not Prozac
Prozac and the New Antidepressants
Prozac Backlash
Prozac Diary
Prozac Nation
Puppy Chow Is Better Than Prozac
Raising a Moody Child
Self-Coaching
Songs from the Black Chair
Speaking of Sadness
Student Depression
Subordination and Defeat
Sunbathing in the Rain
Swing Low
Talking Back to Prozac
The American Psychiatric Publishing Textbook of Mood Disorders
The Anatomy of Melancholy
The Anti-Depressant Fact Book
The Antidepressant Era
The Beast
The Bell Jar
The Corrections
The Cruelty of Depression
The Depressed Child
The Depression Cure
The Emotional Revolution
The Family Silver
The Feeling Good Handbook
The Mood Cure
The Nature of Melancholy
The Noonday Demon
The Postpartum Effect
The Secret Strength of Depression
The Van Gogh Blues
The Van Gogh Blues
Undercurrents
Understanding Depression
Undoing Depression
Unholy Ghost
Unstuck
What the Birds See
When a Parent is Depressed
When Nothing Matters Anymore
When Words Are Not Enough
Why Are You So Sad?
Writing Through the Darkness
 
Self-Help Groups
 
Resources
Basic Information
Introduction and Types of DepressionRelated Disorders / ConditionsHistorical and Current UnderstandingsBiology, Psychology and SociologyTreatment - Medication and PsychotherapyAlternative Medicine and Self-Help ResourcesSpecial IssuesReferences
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Anxiety Disorders
Bipolar Disorder
Suicide
Addictions: Alcohol and Substance Abuse
Pain Management
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